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Tobacco Cessation

Smoking Cessation Interventions

This map provides structured access to an up to date, robust body of secondary evidence on interventions surrounding cessation of tobacco use, as per areas 2-4 of The Welsh Government Tobacco Control Action Plan for Wales. Sources included in the map may provide evidence which addresses the following question: what interventions are effective for smoking cessation?

Date of last search: June 2026.  Next update due: June 2027

How to use this map:  

Reviews and guidelines meeting the map’s inclusion criteria have been categorised by population group and intervention type, and displayed digitally on the heat map. Reviews may appear in several categories if they include, for example, research on multiple types of intervention or multiple population groups. 

The settings in which relevant interventions included in the reviews have been undertaken have been recorded, along with the relevant outcomes measured in the review. You can use the filter boxes at the top of the map to filter the heat map to only show reviews which include relevant studies conducted in particular settings, or reviews that include studies measuring a particular outcome. 

You can click into each box on the heat map to display the list of reviews/guidelines that include evidence within that category, and then further click into each reference to view a summary page for that particular review. The summary pages for each review contain information such as the review aims, findings and conclusions, taken directly from the publication.

We have not conducted any of our own synthesis or interpretation of the findings, but rather have displayed the original authors findings and conclusions so that those viewing the map can see a snapshot of the research, to decide whether they may want to explore the source further. Only review findings relevant to this particular map topic have been categorised, so you may find the reviews cover a broader range of topics, and include additional information that did not meet this map’s inclusion criteria. 

Further information about how the maps are developed and the trusted sources we consult can be found in the About section. 
 
Definitions of the population groups, intervention types, settings and outcomes used to categorise evidence in this map are available in our Glossary.

Map limitations: 

The map is designed to point users in the direction of research evidence that has been synthesised in a way which we know to be methodologically robust, and therefore may be a more reliable base upon which to start thinking about informing decisions. However, our searches are targeted and not exhaustive or comprehensive. Reviews within it should be used as part of a wider strategy for gathering evidence, and not used solely as the basis for decision making, without further interrogation and examination into their applicability for Wales. 

As the map only includes secondary evidence synthesis from a limited range of sources, users should note that new or more innovative interventions which have not yet been subject to robust evidence synthesis may also have not been included. The limited range of sources searched make it likely that additional comprehensive searches of bibliographic databases would identify a wider range of reviews. We would advise that additional reviews you identify be critically appraised to confirm their methodological quality.  

Please note, you may need to scroll horizontally to see all the categories of evidence in the table.

Population Groups

Interventions

Adults Children & Young adults General Population Current / previous history of substance misuse Pre existing health condition Pregnancy/ post-partum Black, Asian and Minority Ethnic populations Military/ ex military Prisoner/ ex prisoner Homeless
Bupropion

Bupropion - Adults

Bupropion - Pre existing health condition

Bupropion - Prisoner/ ex prisoner

Varenicline

Varenicline - Adults

Varenicline - Pre existing health condition

Varenicline - Prisoner/ ex prisoner

Cytisinicline (Cytisine)

Cytisinicline (Cytisine) - Children & Young adults

Cytisinicline (Cytisine) - General Population

Cytisinicline (Cytisine) - Military/ ex military

Cytisinicline (Cytisine) - Prisoner/ ex prisoner

Nicotine Replacement Therapy

Nicotine Replacement Therapy - Adults

Nicotine Replacement Therapy - Pre existing health condition

Nicotine Replacement Therapy - Pregnancy/ post-partum

Nicotine Replacement Therapy - Prisoner/ ex prisoner

Other Pharmacotherapies

Other Pharmacotherapies - Prisoner/ ex prisoner

Nicotine pouches

Nicotine pouches - Children & Young adults

Nicotine pouches - General Population

Nicotine pouches - Current / previous history of substance misuse

Nicotine pouches - Pre existing health condition

Nicotine pouches - Pregnancy/ post-partum

Nicotine pouches - Black, Asian and Minority Ethnic populations

Nicotine pouches - Military/ ex military

Nicotine pouches - Prisoner/ ex prisoner

Nicotine pouches - Homeless

Electronic Nicotine Delivery System

Electronic Nicotine Delivery System - Military/ ex military

Electronic Nicotine Delivery System - Prisoner/ ex prisoner

Alternative smoking cessation therapies

Alternative smoking cessation therapies - Adults

Alternative smoking cessation therapies - Current / previous history of substance misuse

Alternative smoking cessation therapies - Pre existing health condition

Alternative smoking cessation therapies - Black, Asian and Minority Ethnic populations

Alternative smoking cessation therapies - Military/ ex military

Alternative smoking cessation therapies - Prisoner/ ex prisoner

Alternative smoking cessation therapies - Homeless

Universal Smoking Cessation Interventions

Universal Smoking Cessation Interventions - General Population

Universal Smoking Cessation Interventions - Current / previous history of substance misuse

Universal Smoking Cessation Interventions - Black, Asian and Minority Ethnic populations

Universal Smoking Cessation Interventions - Military/ ex military

Universal Smoking Cessation Interventions - Prisoner/ ex prisoner

Universal Smoking Cessation Interventions - Homeless

Behaviour Support

Behaviour Support - Adults

Behaviour Support - General Population

Behaviour Support - Pre existing health condition

Behaviour Support - Pregnancy/ post-partum

Behaviour Support - Prisoner/ ex prisoner

Cognitive Behaviour Therapy

Cognitive Behaviour Therapy - Black, Asian and Minority Ethnic populations

Cognitive Behaviour Therapy - Prisoner/ ex prisoner

Self-Help Materials

Self-Help Materials - Prisoner/ ex prisoner

Motivational Interviewing

Motivational Interviewing - Black, Asian and Minority Ethnic populations

Motivational Interviewing - Prisoner/ ex prisoner

Other Psychosocial Therapies

Other Psychosocial Therapies - Prisoner/ ex prisoner

Multicomponent Interventions

Multicomponent Interventions - Adults

Multicomponent Interventions - General Population

Multicomponent Interventions - Pre existing health condition

Multicomponent Interventions - Pregnancy/ post-partum

Multicomponent Interventions - Prisoner/ ex prisoner