Familial breast cancer: classification, care and managing breast cancer and related risks in people with a family history of breast cancer

NICE (2023)

NICE - CG164

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Evidence Categories

• Care setting: Healthcare Setting
• Care setting: Secondary Care
• Care setting: Other settings
• Care setting: Primary care
• Population group: Women
• Intervention: Risk Assessment
• Intervention: Genetic Testing
• Outcome: Screening: Uptake of breast cancer screening

Type of Evidence

Guidance

Overview

This guideline covers care for people with a family history of breast, ovarian or another related (prostate or pancreatic) cancer. It aims to improve the long-term health of these families by describing strategies to reduce the risk of and promote early detection of breast cancer (including genetic testing and mammography). It also includes advice on treatments (tamoxifen, raloxifene) and surgery (mastectomy).

Recommendations

This guideline includes recommendations on:

• clinical significance of a family history of breast cancer
• information and support
• care of people in primary care
• care of people in secondary care and specialist genetic clinics
• genetic testing
• surveillance and strategies for early detection of breast cancer
• risk reduction and treatment strategies